In September, 2009, 51 samples of lakes as well as 8 of springs and 12 of wells were studies from Lake Guaizi Geological Park in Badain Jaran Desert. The result demonstrated that almost all lakes from southeast edge to hinterland area showed Sulfate-Carbonate-Chloride type. The southeast edge has the most complex type, mainly contained Na⁺, Cl^-, SO₄^2-. It formed into three sub-types for different contents of Ca²⁺ and Mg²⁺, which attributed to different total dissolved solids. One of the subtype, had high TDS and without Ca²⁺, Mg²⁺ also appeared in north, which seemed to be one type just non-sequential distribution, however, they had huge differences. After a comprehensive analysis, it showed that spatial variation of desert lakes mainly formed by climate, and partly by local precipitation directly or indirectly, and groundwater recharge may be other factor. Compared characteristics of water chemistry among the different part of south and north lake, it showed that the supply source of the hinterland was more unstable than that of southeast, which might be drived by climate drying and warming.