As one of the most famous reservoirs with an ecological aquaculture paradigm in China, Lake Qiandaohu(Xin'anjiang Reservoir) has been focused mainly on the stocking of filter-feeding carps such as silver carp and bighead carp while there is still a large information gap on the important piscivorous fish species. In recent years, due to the impacts such as overfishing and habitat fragmentation, piscivorous fish resources declined significantly. However, piscivorous fish are the top predators of aquatic food webs and play an important role in maintaining the structure and function of aquatic ecosystems. Therefore, in this study, we focused on four dominant piscivorous fish species in Lake Qiandaohu: Culter alburnus, Culter mongolicus, Siniperca knerii and Siniperca scherzeri. From March 2021 to December 2022, we collected fish samples monthly in Lake Qiandaohu and the differentiation characteristics of the life history strategies in terms of age, growth, and reproduction were systematically compared. The results indicated that 2-3 years age was the dominant group for all the four populations, and the proportion of senior individuals was relatively low. In terms of the growth patterns, C. alburnus and C. mongolicus belonged to the positive allometric growth pattern, while S. knerii and S. scherzeri showed negative allometric growth, indicated that Culter and Siniperca in Lake Qiandaohu had different growth patterns. It showed that the four piscivorous fishes had different growth strategies. The condition factor was closely related to reproductive activities. And the condition factor for S. knerii was the highest (1.92%±0.03%), followed by S. scherzeri (1.72%±0.02%), C. mongolicus (1.14%±0.01%), while C. alburnus was the lowest (0.97%±0.03%). The difference in condition factor suggested that they might utilize different food resources. The reproductive strategies of the four piscivorous fish species also varied. In terms of the breeding period, the S. knerii and S. scherzeri were relative longer compared to the C. alburnus and C. mongolicus. Regarding fecundity, the relative fecundity of C. alburnus ((254±16) egg/g) and C. mongolicus ((192±10) egg/g) was significantly higher than that of S. knerii ((88±19) egg/g) and S. scherzeri ((88±10) egg/g). Both C. alburnus and C. mongolicus had a unimodal distribution of oocyte diameters, which might be a single-batch spawning type. However, S. knerii and S. scherzeri had a bimodal distribution which suggested that they might be multi-batch spawning types. The variations in reproductive strategies suggest that there might be differentiated. According to the findings, the four piscivorous fishes had been different growth rates, growth patterns, and condition factor as well as the reproductive strategies which might be the key driving factors for the sympatric coexistence of the four piscivorous fish species in Lake Qiandaohu. Our results are of great importance for further understanding the coexistence mechanism of fish species, and will provide guidelines for further conservation and exploitation of the piscivorous fish resource.